Literature summary extracted from

Rettig, W.J.; Su, S.L.; Fortunato, S.R.; Scanlan, M.J.; Raj, B.K.; Garin-Chesa, P.; Healey, J.H.; Old, L.J.
Fibroblast activation protein: purification, epitope mapping and induction by growth factors (1994), Int. J. Cancer, 58, 385-392.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.4.21.B28	95000	-	1 * 95000 + 1 * 105000, SDS-PAGE	Homo sapiens
3.4.21.B28	105000	-	1 * 95000 + 1 * 105000, SDS-PAGE	Homo sapiens
3.4.21.B28	400000	-	above 400000 Da, complex, gel filtration	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.B28	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.4.21.B28	-	Homo sapiens

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.B28	bone	malignant mesenchymal cells	Homo sapiens	-
3.4.21.B28	fibroblast	reactive stromal fibromlasts of breast, colorectal, lung and other epithelial cancers	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.21.B28	Ala-Pro-4-trifluoromethylcoumarin-7-amide + H2O	-	Homo sapiens	Ala-Pro-4 + 7-amino-4-trifluoromethylcoumarin	-	?
3.4.21.B28	Gly-Pro-4-trifluoromethylcoumarin-7-amide + H2O	-	Homo sapiens	Gly-Pro + 7-amino-4-trifluoromethylcoumarin	-	?

Subunits

EC Number	Subunits	Comment	Organism
3.4.21.B28	dimer	1 * 95000 + 1 * 105000, SDS-PAGE	Homo sapiens

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.B28	FAP	-	Homo sapiens
3.4.21.B28	seprase	-	Homo sapiens

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Release 2023.1 (January 2023)